ICCP450/JSSX 2023 Tentative Program


Day 1: Monday, September 25th

  • 17:50-Opening ceremony
  • 18:00-Plenary lecture 1
  • 19:15-20:45Welcome reception

Day 2: Tuesday, September 26th

  • 9:00-11:00Symposium 1-5
  • 11:15-12:15Poster presentation 1
  • 12:30-13:30Luncheon seminar/Break
  • 13:45-15:45Symposium 6-10
  • 16:00-18:30Plenary symposium dedicated to Dr. Tsuneo Omura

Day 3: Wednesday, September 27th

  • 9:00-11:00Symposium 11-14
  • 11:15-12:15Luncheon seminar/Break
  • 12:30-13:30Poster presentation 2
  • 13:30-Excursion (applicants only), Educational sessions
  • 18:00-20:00Banquet (Hotel Grand Hills Shizuoka)

Day 4: Thursday, September 28th

  • 9:00-11:00Symposium 15-19
  • 11:15-12:15Poster presentation 3
  • 12:30-13:30Luncheon seminar/Break
  • 13:45-14:45Plenary lecture 2
  • 15:00-17:00Symposium 20-23

Day 5: Friday, September 29th

  • 9:00-11:00Symposium 24-28
  • 11:15-12:15Plenary lecture 3
  • 12:30-13:30Luncheon seminar/Break
  • 13:45-15:45Symposium 29-32
  • 16:00-Awards ceremony and Closing

* Schedules are subject to change.

Scientific program

Plenary lectures

Plenary lecture 1

  • R. Scott Obach (Pfizer, USA)
  • An improved approach to P450 reaction phenotyping
  • Chair: Kiyomi Ito (Musashino University, Japan)

Plenary lecture 2

  • Emily Scott (University of Michigan, USA)
  • Structures of human P450 drug targets informative in drug design
  • Chair: Kouichi Yoshinari (University of Shizuoka, Japan)

Plenary lecture 3

  • Osami Shoji (Graduate School of Science, Nagoya University, Japan)
  • Biotransformation of non-native substrates by cytochrome P450s utilizing their substrate misrecognition triggered by decoy molecules
  • Chair: Shingo Nagano (Tottori University, Japan)

Plenary session

Remembering Tsuneo Omura: A beloved mentor and a leader in cytochrome P450 and biochemistry

Chairs: Masahiko Negishi (NIEHS/NIH, USA),
Yasushi Yamazoe (Tohoku University, Japan)


  • 1. F. Peter Guengerich (Vanderbilt University, USA)
  • Mechanisms and kinetics of P450s involved in steroid oxidations
  • 2. Bon-Chu Chung (Academia Sinica/China Medical University, Taiwan)
  • Steroidogenic cytochromes P450 and beyond
  • 3. Ulrich M Zanger (Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Germany)
  • About a marathon in P450 pharmacogenetics.
  • 4. Ken-ichirou Morohashi (Graduate School of Medicine, Kurume University, Kurume, Japan)
  • Is Ad4BP almighty?


  1. Case study on human disproportionate metabolite and its prediction
  2. Frontiers of drug metabolism/toxicity studies using novel in vitro and in silico evaluation systems
  3. Application of biomarkers for prediction of drug metabolism and toxicity, and diagnosis
  4. Current trends in the establishment and implementation of new regulatory guidelines related to pharmacokinetics
  5. Use and regulation of biomarkers in drug development
  6. Rising to the challenge: First-in-human dose determination of new therapeutic modalities
  7. Future perspectives in transporter-driven drug development
  8. Single-cell analytical techniques to visualize detailed pharmacokinetics
  9. DDS development strategies for the creation of innovative drugs
  10. Drug absorption from zero: Keys to successful PBPK modeling and simulation of oral drug absorption
  11. Lymphatic and glymphatic system from a perspective of drug development and clinical therapeutics
  12. Comprehension of the present and future of systems modeling in drug discovery -Bridging from the traditional model analysis to the latest research-
  13. Recent trends in MPS development and its applications to drug discovery -What is happening toward industrial implementation and regulatory acceptance in Japan?-"
  14. Basic course of pharmacokinetics on cross-disciplinary
  15. Animal models to predict drug metabolism and toxicity in human
  16. Advance technologies in DMPK research for drug development (IQ consortium symposium)
  17. Neonicotinoids and P450: Metabolism of neonicotinoids in insects, fungi, vertebrates, and humans
  18. Phase II reaction: Its physiological and toxicological functions
  19. Biophysical techniques for P450 studies
  20. P450 across the plant, insect, and microbial systems
  21. New horizons in nuclear receptor research: Novel molecular mechanisms and beyond
  22. The power of metalloenzymes: Insights from model complexes and beyond
  23. Innovations in P450 engineering: Recent advances and future directions
  24. Mechanisms and dynamics of P450
  25. Structure and chemistry of the P450 system
  26. Beyond bone health: Development of novel vitamin D derivatives and vitamin D hydroxylases
  27. Oxygenase in natural product biosynthesis
  28. Breaking down boundaries: Exploring non-P450 oxygenase
  29. Sustainability, biomarker, and bioremediation: The role of cytochrome P450
  30. P450, ADMET, and AI
  31. JSSX-organized Asia-pacific symposium #1: Drug oxidation and metabolism in pharmacology/toxicology
  32. JSSX-organized Asia-pacific symposium #2: Drug transporter research in Asia-Pacific
  33. JSSX awardee presentation

* Session titles are tentative.